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In culture, it thrives only as a plasmodium with thousands of haploid nuclei in one cell. filosa genome is the first foraminiferal genome to be deciphered.The professional phagocyte Dictyostelium discoideum is a simple eukaryotic microorganism, whose natural habitat is deciduous forest soil and decaying leaves, where the amoebae feed on bacteria and grow as separate, independent, single cells.The latter functions, like the JH2 domain of metazoan JAKs, as a negative regulator of the kinase domain.

Also, changes in the external p H were sensed by the ER as indicated by a p H sensitive ER probe as in wild type.

Rhizaria are a major branch of eukaryote evolution with an extensive microfossil record, but only scarce molecular data are available.

The rhizarian species Reticulomyxa filosa, belonging to the Foraminifera, is free-living in freshwater environments.

When Dictyostelium cells are hyperosmotically stressed, STATc is activated by tyrosine phosphorylation.

Unusually, activation is regulated by serine phosphorylation and consequent inhibition of a tyrosine phosphatase: PTP3.

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